The Flockhart Table | Drug Interactions DB

Enter a generic drug name.
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Select one or more enzymes:

1A2
2B6
2C8
2C9
2C19
2D6
2E1
3A4,5,7

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Substrates 
Inhibitors 
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A Strong inhibitor is one that causes a > 5-fold increase in the plasma AUC values or more than 80% decrease in clearance.
A Moderate inhibitor is one that causes a > 2-fold increase in the plasma AUC values or 50-80% decrease in clearance.
A Weak inhibitor is one that causes a > 1.25-fold but < 2-fold increase in the plasma AUC values or 20-50% decrease in clearance.
View Inhibitor Strengths

FDA inhibitors for in vitro experiments.*

preferred
acceptable
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